Needleman Symposium on Autophagy Research: Jan. 30, 2024
January 8, 2024
Highlighting the exciting work of founders of the Philip and Sima Needleman Center for Autophagy Therapeutics and Research, as well as speakers who are prominent leaders in the field.
Learn about exciting new ideas for how the autophagy pathway can be probed as an appealing and dynamic platform for development of new anti-aging therapies.
The Needleman Symposium is an annual event sponsored by the Philip and Sima Needleman Center for Autophagy Therapeutics and Research at Washington University School of Medicine. The center is a bold initiative dedicated to developing novel therapeutics that harness autophagy — a fundamental cellular pathway that has been implicated in age-dependent degeneration, cognitive decline, atherosclerosis, diabetes, obesity, infections, inflammatory diseases and cancer.
2024 Needleman Autophagy Research Symposium:
Latest Advances and the Future of the Field
Tuesday, January 30, 2024 | 9 a.m. – 1 p.m.
EPNEC Auditorium, Washington University Medical Campus
Master of Ceremony: David H. Perlmutter, MD
Symposium program (PDF) »
Event flyer (PDF)»
9 – 9:15 a.m. | Welcome and Remarks
David H. Perlmutter, MD
Executive Vice Chancellor for Medical Affairs, Washington University
George and Carol Bauer Dean of the School of Medicine
Spencer T. and Ann W. Olin Distinguished Professor
Philip Needleman, PhD
Former Professor and Chairman of the Department of Pharmacology, Washington University
Member of the National Academy of Sciences
Former Chief Scientist and Head of R&D Monsanto/Searle/Pharmacia; Former Interim President of Donald Danforth Plant Science Center; Former Interim CEO of the St Louis Science Center
9:15 – 9:30 a.m. | Overview of the Field of Autophagy
David H. Perlmutter, MD
Executive Vice Chancellor for Medical Affairs, Washington University
George and Carol Bauer Dean of the School of Medicine
Spencer T. and Ann W. Olin Distinguished Professor
9:30 – 10:30 a.m. | Molecular Mechanisms and Pathophysiological Roles of Autophagy
Noboru Mizushima, MD, PhD
Professor, Department of Biochemistry and Molecular Biology,
Graduate School and Faculty of Medicine, The University of Tokyo
10:30 – 10:45 a.m. Break
10:45 – 11:30 a.m. | Rescuing Lysosomal Defects in Neurodegenerative Diseases
Celeste Karch, PhD
Professor of Psychiatry, Washington University
Biomarker Core Leader, Knight Alzheimer Disease Research Center (ADRC)
Scientific Director, Dominantly Inherited Alzheimer Network (DIAN)
Associate Director, Dominantly Inherited Alzheimer Network (DIAN)
11:30 a.m. – 12:15 p.m. | Inducing Hepatocyte Fasting-like Responses to Treat Metabolic Disease
Brian DeBosch, MD, PhD
Associate Professor of Pediatrics, Gastroenterology, Hepatology and Nutrition, Washington University
12:15 p.m. | Closing Remarks
David H. Perlmutter, MD
Executive Vice Chancellor for Medical Affairs, Washington University
George and Carol Bauer Dean of the School of Medicine
Spencer T. and Ann W. Olin Distinguished Professor
Please register to attend
Registration for this event has closed. Please contact contact Oscar Diaz Ruiz at doscar@wustl.edu if you have questions or would like more information.