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Research Labs

Washington University School of Medicine faculty, trainees, students and staff collaborate across fields in a dynamic and driven research community.

Explore research Profiles

Profiles is a new knowledge base of faculty and departmental research expertise and interests at the School of Medicine. The system is currently in its pilot phase, and your feedback is welcome!

SEARCH PROFILES

Find labs by department

Basic science research provides an essential foundation for progress in medical care. Through this research, we learn about the biological, genetic and molecular mechanisms that impact our health and wellbeing.


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Allergy & Immunology

Andrew L. Kau, MD, PhD
Research Interests: Microbiota effects on the immune system

Anesthesiology

Gustav Akk, PhD
Research Interests: GABAA and nicotinic acetylcholine receptors

Walter Boyle, MD
Research Interests: Vascular smooth muscle contraction and relaxation

Michael Bruchas, PhD
Research Interests: GPCRS in neural circuits

Yu-Qing Cao, PhD
Research Interests: Migraine Research

Zhou-Feng Chen, PhD
Research Interests: Itch

Alex S. Evers, MD
Research Interests: Protein chemistry of GABAA receptors to identify and characterize drug binding sites

N. Gautam, PhD
Research Interests: Subcellular optogenetics

Robert Gereau, PhD
Research Interests: Cellular and molecular changes in chronic pain

Jason Held, PhD
Research Interests: Redox Signaling & Proteomics

Richard Hotchkiss, MD
Research Interests: Therapeutic approaches to sepsis

Hongzhen Hu, PhD
Research Interests: Pain and itch sensations in the skin

Brian Kim, MD
Research Interests: Skin barrier dysfunction, inflammation, and itch

Cristopher Lingle, PhD
Research Interests: Physiological roles of the BK channel

Qin Liu, PhD
Research Interests: Itch

DP Mohapatra, PhD
Research Interests: Chronic pain associated with metastatic bone cancers

Jose Moron-Concepcion, PhD
Research Interests: Opioid Addiction and Pain

Cristina de Guzman Strong, PhD
Research Interests: Morphogenesis and Homeostasis of functional tissue barriers

Audiology & Communication Sciences

Richard A. Chole, MD, PhD
Research Interests: Mechanisms of tissue destruction in chronic otitis due to bacterial biofilms

Brian T. Faddis, PhD
Research Interests: Cellular and molecular mechanisms associated signal transduction in the auditory system

Nancy Tye-Murray, PhD
Research Interests: Cognitive functions underlying speech recognition and audiovisual integration

Biochemistry & Molecular Biophysics

Gregory R. Bowman, PhD
Research Interests: Mechanisms of Allostery

Peter M. Burgers, PhD
Research Interests: DNA replication and DNA damage response mechanisms in Saccharomyces cerevisiae

John A. Cooper, MD, PhD
Research Interests: Molecular mechanisms of cell motility and cytoskeleton assembly

Elliot L. Elson, PhD
Research Interests: Mechanical studies on Cells and Tissues

William A. Frazier, PhD
Research Interests: Function, structure and mechanism of thrombospondin-1 (TSP1)

Carl Frieden, PhD
Research Interests: Protein Folding

Eric Galburt, PhD
Research Interests: Biophysics of Transcription Initiation

Michael J. Greenberg, PhD
Research Interests: Molecular Motors and Mechanobiology

Kathleen Hall, PhD
Research Interests: RNA Research

Maxene Ilagan, PhD
Research Interests: Mechanism of Notch signaling, Molecular imaging, Assay development, High Throughput Screening

James W. Janetka, PhD
Research Interests: Drug discovery

Alexander Kozlov, PhD
Research Interests: Macromolecular assemblies and protein-nucleic acid complexes

Timothy M. Lohman, PhD
Research Interests: Macromolecular assemblies and protein-nucleic acid complexes

Linda J. Pike, PhD
Research Interests: EGF Receptor research

Andrea Soranno, PhD
Research Interests: Single-Molecule Spectroscopy in Living Cells

Rui Zhang, PhD
Research Interests: Microtubule, cytoskeleton and cell division

Bone & Mineral Diseases

Roberto Civitelli, MD
Research Interests: Cell-cell communication in bone

Clarissa Craft, PhD
Research Interests: The study of microenvironmental determinants of skeletal health

Gabriel Mbalaviele, PhD
Research Interests: Role of inflammasomes in skeletal development and maintenance

Steven Mumm, PhD
Research Interests: Molecular genetics of metabolic bone diseases and skeletal dysplasias

Timothy Peterson, PhD
Research Interests: Genomics, metabolomics, and the quantified self in aging and mental health

Erica Scheller, DDS, PhD
Research Interests: The study of microenvironmental determinants of skeletal health

Steve Teitelbaum, MD
Research Interests: The mechanisms by which osteoclasts degrade bone

Deborah Veis, MD, PhD
Research Interests: Mechanisms of pathological bone loss

Cardiovascular

Dana R. Abendschein, PhD
Research Interests: Thrombosis and neointima formation

C. William Balke, MD
Research Interests: Cardiac calcium homeostasis, SR calcium regulation

Philip M. Barger, MD
Research Interests: Regulation of cardiac transcriptional activity

Sharon Cresci, MD
Research Interests: The pharmacogenomics of cardiovascular disease

Victor G. Davila-Roman, MD, FACC, FASE
Research Interests: Cardiovascular clinical research

Abhinav Diwan, MD, FACC, FAHA
Research Interests: Lysosome biology in cellular stress and homeostasis

Attila Kovacs, MD
Research Interests: Echocardiographic analysis of small animal models of disease

Kory J. Lavine, MD, PhD
Research Interests: Disease mechanisms that contribute to the pathogenesis of heart failure

Douglas L. Mann, MD
Research Interests: Innate immunity, cardiac remodeling, and myocardial recovery

Jeanne M. Nerbonne, PhD
Research Interests: The role of potassium channels in cardiac arrhythmias

Daniel S. Ory, MD
Research Interests: Cholesterol homeostasis in cardiovascular and Niemann-Pick type C disease

Babak Razani, MD, PhD
Research Interests: Mechanisms of atherosclerosis and metabolic diseases (focus on macrophages and the autophagy-lysosome system)

Stacey L. Rentschler, MD, PhD
Research Interests: Programming and Reprogramming Cardiac Conduction

Jean E. Schaffer, MD
Research Interests: Lipotoxicity and cardiac endoplasmic reticulum stress

Joel Schilling, MD, PhD
Research Interests: The role of cytokine signaling in cardiac metabolism

Nathan O. Stitziel, MD, PhD
Research Interests: Human genetics of cardiovascular disease

Carla J. Weinheimer, MS
Research Interests: Animal models of cardiovascular disease

Cell Biology & Physiology

Phyllis I. Hanson, PhD
Research Interests: Intracellular membrane organization and trafficking, ATPases of the AAA+ family of protein remodeling enzymes

John E. Heuser, MD
Research Interests: Electron microscopic visualization

James E. Huettner, PhD
Research Interests: Ion channels gated by receptors for the amino acid L-glutamate

Silvia Jansen, PhD
Research Interests: Actin Cytoskeleton

Vitaly A. Klyachko, PhD
Research Interests: Mechanisms and regulation of synaptic transmission in healthy and disease conditions

Audrey McAlinden, PhD
Research Interests: Cell Biology & Physiology, Cartilage Tissue

Robert P. Mecham, PhD
Research Interests: Extracellular matrix (ECM) secretion and assembly, with a particular focus on ECM proteins important to the cardiovascular system

Robert Mercer, PhD
Research Interests: Molecular and cell biology of ion pumps and transporters in plasma membrane; cell polarity

Michael M. Mueckler, PhD
Research Interests: Molecular biology of glucose transporters

Colin G. Nichols, PhD
Research Interests: Biology of ion channels

David W. Piston, PhD
Research Interests: Glucose homeostasis

Paul H. Schlesinger, MD, PhD
Research Interests: Intracellular ion transport, chloride, protons, mitochondrial channels, phagosome, parasites, bone mineralization

Philip D. Stahl, PhD
Research Interests: Human-Specific Genes

Sheila A. Stewart, PhD
Research Interests: Integrating Communications within the Cancer Environment

Heather L. True, PhD
Research Interests: Prion proteins

Zhongsheng You, PhD
Research Interests: DNA and RNA surveillance systems

Peng Yuan, PhD
Research Interests: Molecular mechanisms of ion channels and transporters that play essential roles in human physiology and disease

Developmental Biology

Irving Boime, PhD
Research Interests: Structure-activity relationships and regulation of the family of human glycoprotein hormones

Angela Bowman, PhD
Research Interests: Regenerative medicine

Douglas F. Covey, PhD
Research Interests: Chemistry and biology of steroids

Aaron DiAntonio, MD, PhD
Research Interests: Molecular mechanisms that control the structure and function of neural circuits in development and disease

Gregory A. Grant, PhD
Research Interests: The structural basis of allosteric control and its long term application to understanding control processes resulting from protein-ligand and protein-protein interactions

Shin-ichiro Imai, MD, PhD
Research Interests: The systemic regulation of aging and longevity in mammals

Aaron N. Johnson, PhD
Research Interests: Understand how morphogens regulate cell form and function during tissue morphogenesis

S. Kerry Kornfeld, MD, PhD
Research Interests: Organismal aging and the biology of metals during growth and development

Kristen Kroll, PhD
Research Interests: Defining gene regulatory networks (GRNs) that control neural cell specification, neurogenesis, and the generation of specific neuronal cell types

Helen McNeill, PhD
Research Interests: Understand how tissue growth and tissue organization are coordinately regulated during normal development, and how loss of this control leads to human disease.

Craig Micchelli, PhD
Research Interests: The basis of stem cell behavior in their native tissue microenvironments

Mayssa Mokalled, PhD
Research Interests: Exploring and promoting spinal cord (SC) repair after injury or disease

Samantha A. Morris, PhD
Research Interests: The in vitro generation of clinically relevant cells, such as neurons, cardiomyocytes, and hepatocytes

Jeanne Nerbonne, PhD
Research Interests: Defining the molecular mechanisms controlling the properties, the cell surface expression, and the functioning of voltage-gated K+ (Kv) channels in the cardiovascular and nervous systems

David M. Ornitz, MD, PhD
Research Interests: In vivo functions of Fibroblast Growth Factors (FGFs), their interactions with other signaling pathways, and their role in tissue regeneration, response to injury, and cancer

Zachary Pincus, PhD
Research Interests: Individual variability, aging, and robustness

Stacey Rentschler, MD, PhD
Research Interests: Developmental programming and reprogramming of conduction tissue; Molecular basis of congenital heart defects

John H. Russell, PhD
Research Interests: CNS (brain and spinal cord) inflammation and pathogenesis in a mouse model of multiple sclerosis

Lilianna (Lila) Solnica-Krezel, PhD
Research Interests: Cellular and molecular genetic mechanisms underlying vertebrate gastrulation

Thorold Theunissen, PhD
Research Interests: Exploring the molecular regulation of pluripotent stem cells and their applications in regenerative medicine

Andrew S. Yoo, PhD
Research Interests: How microRNAs promote neurogenesis and use microRNAs to reprogram cell fates towards neurons

Bo Zhang, PhD
Research Interests: The evolution and adaption of human regulatory networks, with a focus on the impact of these processes on human health and disease

Emergency Medicine

Enyo Ama Ablordeppey, MD, MPH
Research Interests: Ultrasound Section

Christopher R. Carpenter, MD
Research Interests: Evidence Based Medicine

Brian M Fuller, MD, MSCI
Research Interests: Anesthesiology-Critical Care

Richard T. Griffey, MD, MPH, FACEP
Research Interests: Cardiac remodeling and repair

Stacey L. House, MD, MPH
Research Interests: Emergency Care Research Core

Lawrence Lewis, MD
Research Interests: Traumatic brain injury

Tiffany Osborn
Research Interests: Critical Care Medicine

Evan Schwarz
Research Interests: Toxicology

Daniel Theodoro, MD, MSCI
Research Interests: Ultrasound Section

Endocrinology, Metabolism & Lipid Research

Carlos Bernal-Mizrachi, MD
Research Interests: Type 2 diabetes mellitus (Type 2 DM), obesity, hypertension and coronary artery disease (CAD)

Charles A. Harris, MD, PhD
Research Interests: Molecular mechanisms of glucocorticoid action

Jeffrey R. Millman, PhD
Research Interests: In vitro production and study of pancreatic insulin-producing cells from human pluripotent stem cells for use in cellular replacement therapy and drug screening

Maria S. Remedi, PhD
Research Interests: The development and progression of diabetes

Clay F. Semenkovich, MD
Research Interests: Lipid metabolism and how it promotes atherosclerosis in the setting of obesity, insulin resistance and diabetes

Fumihiko Urano, MD, PhD
Research Interests: Developing personalized medicine for juvenile diabetes and genetic forms of diabetes, especially Wolfram syndrome

Gastroenterology

Matthew Ciorba, M.D.
Research Interests: Intestinal inflammation, injury repair and carcinogenesis

Jason C. Mills, M.D., Ph.D.
Research Interests: Cellular and molecular details of adult stem cell biology in the mouse and human GI tract

General Medical Sciences

Joanna Abraham, PhD
Research Interests: Understanding the use of Health Information Technologies (Health IT) and evaluating its impact on effectiveness and efficiency of healthcare team workflows

Chih-Hung Chang, PhD
Research Interests: The integration of methodology and technology to improve patient care quality and safety through efficient yet comprehensive assessment

Randi Foraker, PhD, MA, FAHA
Research Interests: The application of clinical decision support to complement risk scoring in primary care, cardiology, and oncology

Albert M. Lai, PhD
Research Interests: The application of natural language processing, temporal reasoning and information fusion to generate a longitudinal computable phenotype to support clinical trial prescreening

Fuhai Li, PhD
Research Interests: The integration and interpretation of diverse and heterogeneous pharmacogenomics data

Philip R.O. Payne, PhD, FACMI
Research Interests: The use of knowledge engineering and human-computer interaction design principles in order to improve the efficiency of multi-site clinical and translational research programs

Po-Yin Yen, PhD, RN
Research Interests: Applied clinical informatics research to support clinicians adapting to health information technology

Genetics

Barak Cohen, PhD
Research Interests: Computational Biology

Don Conrad, PhD
Research Interests: Human Genetics and Reproductive Biology

Joseph Dougherty, PhD
Research Interests: Genomics of Behavior in Health & Disease

Susan Dutcher, PhD
Research Interests: Genetics, Biochemistry, Microscopy, and Computational Biology

Heather Lawson, PhD
Research Interests: Metabolic traits

Jeffrey Milbrandt, MD, PhD
Research Interests: Axonal integrity and function

Robi Mitra, PhD
Research Interests: Computational Biology

Samantha Morris, PhD
Research Interests: Developmental Biology

Zachary Pincus, PhD
Research Interests: Developmental Biology

Michael Province, PhD
Research Interests: Statistical Genomics

Nancy Saccone, PhD
Research Interests: Human Genetics

Tim Schedl, PhD
Research Interests: Germline Development

James Skeath, PhD
Research Interests: Developmental Biology

Gary Stormo, PhD
Research Interests: The mechanisms of gene regulation

Ting Wang, PhD
Research Interests: The evolution and adaptation of human regulatory networks

Hematology & Oncology

Luis F. Z. Batista, PhD
Research Interests: Induced pluripotent stem cells; Telomere maintenance

Ron Bose, MD, PhD
Research Interests: Her2/neu tyrosine kinase, Genomics of breast cancer, Use of proteomics to study breast cancer cell signaling

Audrey Brenot, PhD
Research Interests: Epithelial-mesenchymal transition (EMT), Immune response, Tumor initiating cells, Cancer biology, Breast cancer

Grant A. Challen, PhD
Research Interests: Hematopoietic stem cells, Leukemia stem cells, Epigenetic modifications

Milan G. Chheda, MD
Research Interests: Epigenetics. Cancer genomics, Cancer stem cells, Glioma

David G. DeNardo, PhD
Research Interests: Immune response, Metastasis, Breast cancer, Pancreatic cancer

Li Ding, PhD
Research Interests: Cancer genomics and proteomics

Todd A. Fehniger, MD, PhD
Research Interests: Innate immunity, Natural killer cell biology, Micro RNAs. Cytokines, Natural killer cell based therapeutics

Malachi Griffith, PhD
Research Interests: Cancer informatics, Bioinformatics, Genomics, Precision medicine, Immunogenomics

Ira M. Hall, PhD
Research Interests: Genetics, Genomics, Bioinformatics

Kian H. Lim, MD, PhD
Research Interests: Inflammation, Innate immunity, Immunotherapy, Tumor-stroma interaction, KRas, IRAK4

Gregory D. Longmore, MD
Research Interests: Epithelia morphogenesis, Cancer metastasis

Leonard B. Maggi, Jr., PhD, MSCI
Research Interests: Tumorigenesis, Nucleolar protein function, Ribosome biogenesis

Christopher A. Maher, PhD
Research Interests: Computational biology, Bioinformatics, Genomics, Cancer

Jieya Shao, PhD
Research Interests: Breast cancer, Molecular mechanisms, Translational research

George P. Souroullas, PhD
Research Interests: Epigenetic mechanisms, B cell lymphoma, Melanoma

Christopher M. Sturgeon, PhD
Research Interests: Embryonic stem cells, Pluripotent stem cells, Hematopoiesis, Developmental Biology

Jason D. Weber, PhD
Research Interests: Cell cycle, Tumor suppressors, Oncogenes

Infectious Diseases

Megan Tierney Baldridge, MD, PhD
Research Interests: Interactions of the intestinal commensal microbiota with viral (such as murine norovirus) and bacterial pathogens, and the regulation of these interactions by the mucosal innate immune system

Jacco Boon, PhD
Research Interests: Influenza A virus

David B. Clifford, MD
Research Interests: HIV neurological disorders, peripheral neuropathy, HIV related dementia,AIDS neurology, progressive multifocal leukoencephalopathy (PML), neurologic infection, multiple sclerosis and Alzheimer’s disease

Michael S. Diamond, MD, PhD
Research Interests: The interface between viral pathogenesis and the host immune response

James M. Fleckenstein, MD
Research Interests: Diarrheal illness and the molecular pathogenesis of enterotoxigenic Escherichia coli (ETEC)

Daniel E. Goldberg, MD, PhD
Research Interests: Malaria and parasitic diseases

Jeffrey P. Henderson, MD, PhD
Research Interests: Bacterial virulence and antibacterial therapeutic strategies

Robyn Klein, MD, PhD
Research Interests: The pathogenesis of neuroinflammatory diseases of the central nervous system (CNS)

Mark J. Miller, PhD
Research Interests: Antigen capture and presentation in the spleen

Makedonka Mitreva, PhD
Research Interests: Neglected tropical diseases (NTDs); the human microbiome

Jennifer A. Philips, MD, PhD
Research Interests: Gaining mechanistic insight into how Mtb alters cellular trafficking, antigen presentation, host cell metabolism and cytokine responses of macrophages and dendritic cells

Haina Shin, PhD
Research Interests: Herpes simplex virus

Gary J. Weil, MD
Research Interests: Filarial nematode parasites that cause important tropical diseases such as lymphatic filariasis and river blindness

Molecular Microbiology

Stephen M. Beverley, PhD
Research Interests: Molecular genetics of protozoan parasites

Michael G. Caparon Jr., PhD
Research Interests: Interaction of pathogenic Gram-positive bacteria and their human hosts

Tamara L. Doering, MD, PhD
Research Interests: Cryptococcal Biology

Mario Feldman, PhD
Research Interests: Microbial Glycobiology

Scott J. Hultgren, PhD
Research Interests: UTI Research

Shabaana Khader, PhD
Research Interests: Mycobacterium tuberculosis

Sebla Kutluay, PhD
Research Interests: Molecular Biology of HIV-1-Host Interactions

Amanda Lewis, PhD
Research Interests: Microbial Glycobiology & Women’s Health

Jennifer Lodge, PhD
Research Interests: Microbial Pathogenesis

David L. Sibley, PhD
Research Interests: Cellular Microbiology of Protozoan Parasites

Christina Stallings, PhD
Research Interests: Mycobacterium tuberculosis

Niraj Harish Tolia, PhD
Research Interests: Pathogenesis of infectious disease

David Wang, PhD
Research Interests: Pathogen Discovery and Infectious Disease Genomics

Nephrology

Feng Chen, PhD
Research Interests: Urogenital diseases, urogenital development, Calcineurin-NFAT, molecular genetics, diabetes insipidus, collecting duct, prostate cancer

Ying Maggie Chen, MD, PhD
Research Interests: Proteinuria; Podocytes; Endoplasmic Reticulum Stress; Renal Fibrosis; Endothelial Cells

Andreas Herrlich, MD, PhD
Research Interests: Breast cancer and kidney disease applications

Jianghui Hou, PhD
Research Interests: Claudins, salt resorption, fluid balance, hypomagnesemia, hypercalciuria, hypochloremia, hypertension, kidney stones

Benjamin D. Humphreys, MD, PhD
Research Interests: The cellular and molecular mechanisms of kidney regeneration and thereby identify new therapeutic strategies for humans suffering from kidney disease

Sanjay Jain, MD, PhD
Research Interests: Kidney development, ureter development, CAKUT, AKI, genomics, neurodevelopment, GDNF, RET, branching morphogenesis, genetics, biobanking, translational research, biomarkers, regeneration, stem cells, bladder regeneration, bladder pain

Mohamed R. Mahjoub, PhD
Research Interests: Cilia, centrosome, microtubule cytoskeleton, ciliopathies, cystic kidney disease, primary cilia dyskinesia, cancer

Jeffrey H. Miner, PhD, FASN
Research Interests: Glomerular basement membrane (GBM), extracellular matrix, Alport syndrome, Pierson syndrome, CAKUT, laminin, collagen, nephrotic syndrome, proteinuria

Neurology

Beau M. Ances, MD, PhD
Research Interests: Developing structural and functional neuroimaging biomarkers of normal aging and neurodegeneration

Randall J. Bateman, MD
Research Interests: Alzheimer’s Disease

Nigel Cairns, PhD, FRCPath
Research Interests: Alzheimer’s Disease

John R. Cirrito, PhD
Research Interests: Relationship between synaptic activtity and amyloid-beta metabolism in Alzheimer’s disease

David B. Clifford, MD
Research Interests: Clinical Neuropharmacology

Anne Maureen Connolly, MD
Research Interests: Pediatric Neurology

Maurizio Corbetta, MD
Research Interests: Brain plasticity in humans

Anne H. Cross, MD
Research Interests: Neuroimmunology

Michael N. Diringer, MD
Research Interests: Adult Neurology

Nico U.F. Dosenbach, MD, PhD
Research Interests: Use-driven brain plasticity in humans

Lawrence N. Eisenman, MD, PhD
Research Interests: Adult Epilepsy Center

Anne Fagan, PhD
Research Interests: Alzheimer’s Disease

Stefanie Geisler, MD
Research Interests: Neuromuscular Disease

David H. Gutmann, MD, PhD
Research Interests: Pediatric Neurology

David Michael Holtzman, MD
Research Interests: Adult Neurology

Mark Jacquin, PhD
Research Interests: Molecular Mechanisms of Trigeminal Development

Paul T. Kotzbauer, MD, PhD
Research Interests: Parkinson’s Disease

Terrance T. Kummer, MD, PhD
Research Interests: Neurocritical Care

Jin-Moo Lee, MD, PhD
Research Interests: Cerebrovascular Disease

Mingjie Li, MD, PhD
Research Interests: Viral Vectors Core

Luigi Maccotta, MD, PhD
Research Interests: Adult Epilepsy Center

Pietro Mazzoni, MD, PhD
Research Interests: Movement Disorders

Timothy Miller, MD, PhD
Research Interests: ALS – Lou Gehrig’s Disease

John Morris, MD
Research Interests: Alzheimer’s Disease

Erik Musiek, MD, PhD
Research Interests: Alzheimer’s Disease

Jeffrey J. Neil, MD, PhD
Research Interests: Pediatric Neurology

Joel S. Perlmutter, MD
Research Interests: Movement Disorders

Steven E. Petersen, PhD
Research Interests: Neuroimaging

Laura Piccio, MD, PhD
Research Interests: Multiple Sclerosis (MS) and neurodegenerative diseases

Brad A. Racette, MD
Research Interests: Movement Disorders

Catherine M. Roe, PhD
Research Interests: Alzheimer’s Disease

Gordon L. Shulman, PhD
Research Interests: Attention, Perception, and Cognition in Adults

Barbara Joy Snider, MD, PhD
Research Interests: Alzheimer’s Disease

Kwee Liu Lin Thio, MD
Research Interests: Cellular neurophysiology, inhibitory glycine receptors, and ketogenic diet

Tom O. Videen, PhD
Research Interests: Brain physiology

Conrad C. Weihl, MD, PhD
Research Interests: Adult Neurology

Michael Wong, MD, PhD
Research Interests: Pediatric Neurology

Gregory F. Wu, MD, PhD
Research Interests: Adult Neurology

Allyson R. Zazulia, MD
Research Interests: Cerebrovascular Disease

John Zempel, MD, PhD
Research Interests: Pediatric Neurology

Neuroscience

Martha Bagnall, PhD
Research Interests: Orientation, movement, and posture

Azad Bonni, MD, PhD
Research Interests: Developmental, Regenerative and Stem Cell Biology

Valeria Cavalli, PhD
Research Interests: Regenerative response of neurons in the peripheral nervous system

James Fitzpatrick, PhD
Research Interests: Cellular Imaging

Harrison Gabel, PhD
Research Interests: Gene regulation

Ashley Morhardt, PhD
Research Interests: Paleoneurology

Michael Nonet, PhD
Research Interests: Neuronal synapse development

Camillo Padoa-Schioppa, PhD
Research Interests: Neuroeconomics

Carlos Ponce, MD, PhD
Research Interests: Perception of vision

Paul Shaw, PhD
Research Interests: Sleep physiology and architecture

David Van Essen, PhD
Research Interests: Cerebral cortex

Jason Yi, PhD
Research Interests: Mechanistic mammalian brain development

Guoyan Zhao, PhD
Research Interests: Transcriptional regulatory networks in the nervous system

Neurosurgery

Albert H. Kim, MD, PhD
Research Interests: Pituitary Center

Eric C. Leuthardt, MD
Research Interests: Neuroprosthetics and Brain Mapping

David D. Limbrick, MD, PhD
Research Interests: Pediatric Neurosurgery

Wilson Z Ray, MD
Research Interests: Spine Service

Keith M. Rich, MD
Research Interests: The role of apoptosis after treatment of glioma cells with DNA-damaging agents

Hiroko Yano, PhD
Research Interests: Molecular mechanisms of neurodegeneration in neurological disorders

Gregory J. Zipfel, MD
Research Interests: Neurological Surgery

Obstetrics & Gynecology

Sarah K. England, PhD
Research Interests: Basic Science Research, Placenta, Premature Birth

Katherine Fuh, MD, PhD
Research Interests: Basic Science Research, Gynecologic Oncology, Translational Research

Ramakrishna Kommagani, PhD
Research Interests: Basic Science Research, Reproductive Endocrinology & Infertility, Translational Research

Kelle H. Moley, MD
Research Interests: Basic Science Research, Placenta, Reproductive Endocrinology & Infertility

Indira Mysorekar, PhD
Research Interests: Basic Science Research, Infection, Placenta, Premature Birth, Translational Research

Celia Santi, MD, PhD
Research Interests: Basic Science Research, Reproductive Endocrinology & Infertility

Yong Wang, PhD
Research Interests: Basic Science Research, Obstetrics & Maternal-Fetal, Premature Birth, Translational Research

Occupational Therapy

Benjamin Philip, PhD
Research Interests: Basic science of how brain controls movement and application of that knowledge to patient rehabilitation

Ophthalmology & Visual Sciences

Usha Andley, PhD
Research Interests: Lens & Cornea

Rajendra Apte, MD, PhD
Research Interests: Retina, Retinal Degeneration & Neovascularization

Steven Bassnett, PhD
Research Interests: Glaucoma & Ocular Hypertension, Lens & Cornea

Ken Blumer, PhD
Research Interests: Cell Biology and Physiology

Andreas Burkhalter, PhD
Research Interests: Anatomy & Neurobiology

Shiming Chen, PhD
Research Interests: Retina, Retinal Degeneration & Neovascularization

Brian Clark, PhD
Research Interests: Retina, Retinal Degeneration & Neovascularization

Joseph Corbo, MD, PhD
Research Interests: Pathology & Immunology

Susan Culican, MD, PhD
Research Interests: Pediatric Ophthalmology

Thomas Ferguson, PhD
Research Interests: Retina, Retinal Degeneration & Neovascularization

Feng Gao, MD, PhD
Research Interests: Biostatistics

Mae Gordon, PhD
Research Interests: Glaucoma & Ocular Hypertension

Didier Hodzic, PhD
Research Interests: Retina, Retinal Degeneration & Neovascularization

Andrew Huang, MD, MPH
Research Interests: Lens & Cornea

Michael Kass, MD
Research Interests: Glaucoma & Ocular Hypertension

Vladimir Kefalov, PhD
Research Interests: Retina, Retinal Degeneration & Neovascularization

Daniel Kerschensteiner, MD
Research Interests: Retina, Retinal Degeneration & Neovascularization

Peter Lukasiewicz, PhD
Research Interests: Retina, Retinal Degeneration & Neovascularization

Todd P. Margolis, MD, PhD
Research Interests: Infectious Diseases

Josh Morgan, PhD
Research Interests: Visual Processing

John Pruett, MD, PhD
Research Interests: Psychiatry, Radiology, and Psychological & Brain Sciences

Rithwick Rajagopal, MD, PhD
Research Interests: Retina, Retinal Degeneration & Neovascularization

Nathan Ravi, MS, PhD, MD, FAAO
Research Interests: Lens & Cornea

Alan Shiels, PhD
Research Interests: Lens & Cornea

Carla Siegfried, MD
Research Interests: Glaucoma

Lawrence Snyder, MD, PhD
Research Interests: Neuroscience

Florentina Soto, PhD
Research Interests: Retina, Retinal Degeneration & Neovascularization

Lawrence Tychsen, MD
Research Interests: Pediatric Ophthalmology

Gregory Van Stavern
Research Interests: Neuro-Ophthalmology

Ralf Wessel, PhD
Research Interests: Neurophysics

Orthopaedic Surgery

Yousef Abu-Amer, PhD
Research Interests: Inflammatory joint diseases

Matthew Dobbs, MD
Research Interests: Pediatric Foot Deformities

Roberta Faccio, PhD
Research Interests: Immune Cells and Osteoclasts

Farshid Guilak, PhD
Research Interests: Osteoarthritis

Spencer Lake, PhD
Research Interests: Musculoskeletal Soft Tissue Mechanics

Audrey McAlinden, PhD
Research Interests: Cartilage Tissue

Regis O’Keefe, MD, PhD
Research Interests: Orthopaedic oncology, sarcoma

M. Farooq Rai, PhD
Research Interests: Osteoarthritis

Linda Sandell, PhD
Research Interests: Gene regulation of extracellular matrix proteins and its influence on the phenotype of cells

Matthew Silva, PhD
Research Interests: Musculoskeletal Structure and Strength, Bone

Simon Tang, PhD
Research Interests: Biological regulation of skeletal matrix quality

Otolaryngology

Pablo Blazquez, PhD
Research Interests: Understanding motor control and balance in the normal and diseased brain

Lisa Davidson, PhD
Research Interests: How perceptual and cognitive abilities interact to determine relative benefits of sensory devices for children with moderate to profound sensorineural hearing loss

Jill Firszt, PhD
Research Interests: Bilateral and unilateral cochlear implants in adults and children, asymmetric hearing and unilateral hearing loss, speech recognition, behavioral and electrophysiologic measures with electrical stimulation and optimization of speech processor mapping

Joel Goebel, MD
Research Interests: Hearing loss, dizziness, balance disorders

Keiko Hirose, MD
Research Interests: Biology of Hearing & Deafness

Tejbeer Kaur, PhD
Research Interests: Neuron-immune interactions along the auditory pathway during development and disease and to understand the contributions of the immune system to neurodegeneration, protection and regeneration in deafened ears

Jeffery Lichtenhan, PhD
Research Interests: Normal and diseased cochlear physiology

Judith Lieu, MD, MSPH
Research Interests: The effects and consequences of hearing loss in children, especially unilateral hearing loss (hearing loss in one ear)

Allison Ogden, MD, FACS
Research Interests: Salivary gland disease, salivary gland stones, sialendoscopy (salivary endoscopy), salivary gland tumors

Kevin K. Ohlemiller, PhD
Research Interests: The role of genetics in age-related hearing loss and noise-induced hearing loss

Jonathan E. Peelle, PhD
Research Interests: Understanding how the brain understands speech, and how this is affected by changes in cognitive and hearing ability

Jay Piccirillo, MD
Research Interests: Sinusitis, Tinnitus, Cancer Comorbidities, Hereditary Hemoorhagic Telangiectasia (HHT)

Sidharth Puram, PhD
Research Interests: Understanding the transcriptional and epigenetic heterogeneity underlying head and neck cancers.

Mark A. Rutherford, PhD
Research Interests: Sensory encoding and how sound is transduced by the inner ear

Alec Salt, PhD
Research Interests: Local drug delivery to the inner ear

Lavinia Sheets, PhD
Research Interests: How specific pathological changes occur in hair cells exposed to noise by defining the dynamic cellular processes that lead to hair-cell synapse loss and hair-cell death

Nancy Tye-Murray, PhD
Research Interests: Fostering successful spoken language communication for both adults and children

Michael Valente, PhD
Research Interests: Cellular and molecular mechanisms of auditory signal transduction, sensory cell death and regeneration and development and how communication disorders can be measured, treated and overcome

Mark Warchol, PhD
Research Interests: The development and regeneration of sensory receptors and afferent neurons in the inner ear

Jose Zevallos, MD
Research Interests: Head and neck squamous cell carcinoma

Pathology & Immunology

Paul Allen, PhD
Research Interests: Immunobiology, T Cell Receptor Research

Maksym N Artyomov, PhD
Research Interests: Systems Immunology

Joseph C. Corbo, MD, PhD
Research Interests: Neurobiology and Genomics

Erika C Crouch, MD, PhD
Research Interests: Surfuctant Protein D

Gautam Dantas, PhD
Research Interests: Microbiology

Jeffrey Gordon, MD
Research Interests: Gnotobiotic animal models; human gut microbial communities

Nima Mosammaparast, MD, PhD
Research Interests: DNA Repair

Eugene Oltz, PhD
Research Interests: Lymphocyte Development and Cancer Research

Jacqueline Payton, MD, PhD
Research Interests: Molecular Diagnostics Laboratory

Gwendalyn J Randolph, PhD
Research Interests: The lymphatic vasculature

S. Joshua Swamidass, MD, PhD
Research Interests: Drug metabolism, drug discovery, and translational research

Steven Teitelbaum, MD
Research Interests: Obesity

Emil Unanue, MD
Research Interests: Antigen Processing & Presentation

Pediatrics

Avraham Beigelman, MD
Research Interests: Childhood asthma and food allergy

Francis Sessions Cole, III, MD
Research Interests: Genetic mechanisms underlying neonatal respiratory distress syndrome

Megan A. Cooper, MD, PhD
Research Interests: Mechanisms of immune cell control, including regulation of natural killer cell activation and mechanisms driving pediatric immune-mediated disease

Brian DeBosch, MD, PhD
Research Interests: Hepatic and enterocyte determinants of metabolic syndrome and non-alcoholic fatty liver disease

Mary C. Dinauer, MD, PhD
Research Interests: The superoxide-generating leukocyte NADPH oxidase

Allan Doctor, MD
Research Interests: The physiology of acquired red cell injury, on development of a novel bio-synthetic artificial red cell, and on translational transfusion medicine in the ICU setting

Todd Druley, MD, PhD
Research Interests: The role of germline genetic variation in patient-specific inducible pluripotent stem cell models in predisposing to pediatric cancer

Thomas Ferkol, MD
Research Interests: The effects of viral infections on the microbiota, inflammation, lung function, and structural changes in the cystic fibrosis airway in infants

Anthony R. French, MD, PhD
Research Interests: Rheumatology and the interface between the host innate immune system and large double-stranded DNA viruses and how interactions at this interface may influence the initiation of inappropriate autoimmune responses in rheumatic diseases

Stuart Friess, MD
Research Interests: Studying the effects of delayed secondary insults on white matter injury following traumatic brain injury

Stephanie A. Fritz, MD, MSCI
Research Interests: The epidemiology, treatment, and prevention of pediatric methicillin-resistant Staphylococcus aureus infections

Misty Good, MD, MS
Research Interests: The cellular and molecular mechanisms involved in the development of necrotizing enterocolitis (NEC)

Lori R. Holtz, MD, MSPH
Research Interests: Disorders of the developing childhood gut and employs metagenomics, virology, and epidemiology to begin to define the stool virome in health and disease

Amjad Horani, MD
Research Interests: Airway epithelial cell pathogenesis including primary ciliary dyskinesia (PCD)

Keith A. Hruska, MD
Research Interests: Chronic kidney disease-mineral bone disorder (CKD-MBD) syndrome, chronic kidney disease (CKD), and mechanisms of its complications

Paul W. Hruz, MD, PhD
Research Interests: Endocrine disorders especially diabetes mellitus

David A. Hunstad, MD
Research Interests: The interactions of pathogenic Gram-negative bacteria with their hosts

Patrick Y. Jay, MD, PhD
Research Interests: Congenital heart disease

Jeffrey Magee, MD, PhD
Research Interests: Childhood and adult leukemia

Amit M Mathur, MD, MRCP
Research Interests: The study of brain injury and neuroprotection in the neonate

S. Celeste Morley, MD, PhD
Research Interests: How elements of the actin cytoskeleton regulate immune cell shape and motility, and how impairments in motility then alter immune cell development and activation

Audrey R. Odom, MD, PhD
Research Interests: Basic molecular and cellular biology of the malaria parasite

Clifford J. Luke, PhD
Research Interests: The interplay between cell stress (e.g., infection, hypoxia, hyperoxia, and electrolyte disturbances), protease activation, and serpin blockade.

Stephen C. Pak, PhD
Research Interests: The interplay between cell stress (e.g., infection, hypoxia, hyperoxia, and electrolyte disturbances), protease activation, and serpin blockade.

Kimberly S. Quayle, MD
Research Interests: Fluid Therapy and Cerebral Injury in Pediatric Diabetic Ketoacidosis

David A. Rosen, MD, PhD
Research Interests: Basic pathogenic mechanisms of Klebsiella pneumoniae

Joshua B. Rubin, MD, PhD
Research Interests: Basic and translational neuro-oncology

Scott Saunders, MD, PhD
Research Interests: Understanding the molecular basis of development

Laura Schuettpelz, MD, PhD
Research Interests: Hematopoietic stem cells

Alan L. Schwartz, MD, PhD
Research Interests: The cell and molecular biology of intracellular protein targeting and degradation

Shalini Shenoy, MD
Research Interests: The development of safer less toxic methods of hematopoietic stem cell transplantation in children

Gary A. Silverman, MD, PhD
Research Interests: The interplay between cell stress (e.g., infection, hypoxia, hyperoxia, and electrolyte disturbances), protease activation, and serpin blockade.

Philip C. Spinella, MD, FCCM
Research Interests: Critical illness related pathophysiology of blood cells and proteins during critical illness

Stephen Stone, MD
Research Interests: Regenerative Medicine, Restorative Medicine, ER Stress Diseases, Wolfram Syndrome, Insulin Resistance

Phillip I. Tarr, MD
Research Interests: Enteric infections and gut microbiology

Zachary A. Vesoulis, MD
Research Interests: The interaction between the brain and the cardiovascular system, in both preterm and term infants

Jennifer A Wambach, MD
Research Interests: Genetic Mechanisms Underlying Neonatal Respiratory Distress Syndrome

David B. Wilson, MD, PhD
Research Interests: Cellular differentiation, organ development, and tumorigenesis

Kristine Wylie, PhD
Research Interests: The microbiome and infectious diseases during pregnancy

Physical Therapy

W. Todd Cade, PT, PhD
Research Interests: Mechanisms and treatments for skeletal muscle and heart abnormalities in metabolic disease

Gretchen A. Meyer, PhD
Research Interests: Effects of fat on muscle function and how that effect is regulated at cellular and tissue levels

Michael Mueller, PT, PhD, FAPTA
Research Interests: Movement and metabolic factors that contribute to injury and tissue adaptation in people with chronic diseases

Pulmonary & Critical Care Medicine

Thomas Brett, PhD
Research Interests: Pulmonary and Critical Care, Investigation of Membrane Excitability Diseases

Michael E. Hughes, PhD
Research Interests: The function and mechanism of tissue-specific gene expression

Psychiatry

Deanna Barch, PhD
Research Interests: Psychological & Brain Sciences

Kevin J. Black, MD
Research Interests: Neuroimaging methods development including pharmacological fMRI

Kelly N. Botteron, MD
Research Interests: NeuroImaging Laboratories

Dorothy Van Buren, PhD
Research Interests: Lifestyle interventions for youth with Type 2 Diabetes and their families, psychological treatments for Binge Eating Disorder, pediatric obesity, evidence based treatments for eating disorders

Patricia Cavazos-Rehg, PhD
Research Interests: Health Risks and Behavior in Social Media

Li-Shiun Chen, MD
Research Interests: Psychiatric oncology, psychiatric genetics and cancer prevention

Theodore J. Cicero, PhD
Research Interests: Prescription Drug Abuse

C. Robert Cloninger, MD
Research Interests: Science of Well-Being

John N. Constantino, MD
Research Interests: Intellectual and Developmental Disabilities Research Center

Carlos Cruchaga, PhD
Research Interests: Neurodegenerative Diseases

Nuri B. Farber, MD
Research Interests: Animal Neuropathology

Ellen Fitzsimmons-Craft, PhD
Research Interests: Etiology and maintenance of body dissatisfaction and disordered eating

Kirsten Gilbert, PhD
Research Interests: Self-control and over-control in children

Richard Grucza, PhD, MPE
Research Interests: Policy and other environmental influences on substance use disorders, alcohol use and smoking

Laura Jean Bierut, MD
Research Interests: Environmental and genetic contributions to smoking behaviors, addiction and other psychiatric and medical illnesses

Celeste Karch, PhD
Research Interests: Neurodegeneration

Eric Lenze, MD
Research Interests: Brain, body, and mind health through deprescribing

Joan Luby, MD
Research Interests: Early Emotional Development

Daniel Mamah, MD, MPE
Research Interests: Neuroimaging, clinical and epidemiologic research geared towards the early identification and management of psychiatric illnesses

Steven Mennerick, PhD
Research Interests: To understand control of neuronal excitation and inhibition by neurotransmitters in the central nervous system.

Radiation Oncology

Abdel Kareem Azab, PhD
Research Interests: Radiation Treatment for Cancers

Aadel Chaudhuri, MD, PhD
Research Interests: Circulating Tumor DNA

Hong Chen, PhD
Research Interests: Ultrasound Techniques

David T. Curiel, MD, PhD
Research Interests: Adenovirus for Molecular Medicine applications

Arash Darafsheh, PhD
Research Interests: Optical Imaging and Dosimetry Lab

Carl DeSelm, MD, PhD
Research Interests: Chimeric Antigen Receptor (CAR) T cell therapy

Dennis E. Hallahan, MD, FASTRO
Research Interests: Radiation Treatment for Cancers

Geoffrey Hugo, PhD
Research Interests: Imaging and image guidance as it applies to radiation therapy

Hua Li, PhD
Research Interests: The development of advanced image processing, machine learning, and pattern recognition methods for the improvement of medical imaging applications

Stephanie Markovina, MD, PhD
Research Interests: Biomarkers and Novel Therapeutic Targets to Personalize Cancer Care

Buck Rogers, PhD
Research Interests: The development of novel radioactive probes for imaging and therapy with the end goal of impacting patient care

Julie K. Schwarz, MD, PhD
Research Interests: The biologic pathways that regulate treatment response in cervical cancer

Xiaowei Wang, PhD
Research Interests: RNA Research

Deshan Yang, PhD
Research Interests: Medical Imaging and Health Informatics

Tiezhi Zhang, PhD
Research Interests: Advanced X-Ray Imaging

Radiology

Samuel Achilefu, PhD
Research Interests: Design, development, and biochemical evaluation of molecular imaging agents and drugs in cells and living organisms

Joseph J.H. Ackerman, PhD
Research Interests: Magnetic Resonance of Intact Biological Systems

Tammie Benzinger, MD, PhD
Research Interests: Neuroradiology

Mikhail Berezin, PhD
Research Interests: Contrast agents, peripheral neuropathy, hyperspectral imaging

G. Larry Bretthorst, PhD
Research Interests: Bayesian Probability Theory

Joseph Culver, PhD
Research Interests: Non-invasive optical measurements for both functional- and molecular- biological imaging

Robert J. Gropler, MD
Research Interests: PET-related research of the CV system

Daniel Marcus, PhD
Research Interests: Neuroinformatics

Yuan-Chuan Tai , PhD
Research Interests: Development of novel molecular imaging systems and technologies for clinical, preclinical and plant imaging applications

Surgery

William G. Hawkins, MD
Research Interests: SPORE in Pancreatic Cancer

WenJun Li, PhD
Research Interests: Thoracic Immunobiology Lab

Susan E. Mackinnon, MD
Research Interests: Peripheral Nerve Surgical Research Laboratories

Mohamed Zayed, MD, PhD
Research Interests: Diabetes Research